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Certificate of Upstream Bioprocessing (3 Days)
The course is aimed at early career professionals and anyone who wants to develop an understanding of upstream bio-manufacturing techniques and processes.
This 3-day course consists of 6 lectures, enhanced with practical demonstrations using bench-scale, pilot-scale, and single-use bioreactors. In particular, attendees will gain hands-on fermentation experience using a 30L-scale, stainless steel stirred tank bioreactor. The course includes the set-up, steam sterilisation in place (SIP), inoculation, monitoring and harvest of a 30L yeast fermentation.
On completion of the course, the attendees will be presented with a ‘Certificate of Upstream Bioprocessing’ issued by IBioIC.
Learning outcomes
Obtain an up-to-date overview of microbial and mammalian cell cultivation in the field of bio-manufacturing.
Know the considerations and possible challenges of upstream bioprocessing scale-up.
Be aware of various cell types, cell metabolism, fermentation modes and bioreactor types.
Be aware of the importance of preparation, sterilisation, monitoring and quality control of fermentation process.
Develop hands-on fermentation skills through practical experience using a stainless-steel pilot bioreactor.
Familiarise with sampling techniques used in fermentation and biomass quantification methods.
Learn and apply fundamental aseptic and sampling techniques.
Who will benefit
Operatives, scientists, engineers, graduates, technical managers, especially those in their early career in fermentation and upstream bioprocessing.
Anyone who would like to gain an insight into the theoretical and practical aspects of bio-manufacturing.
Course Dates:
23 - 25 September 2025
17 - 19 March 2026
To find out more and book a place, email scaleup@ibioic.com
Mastering Protein Purification using Chromatography Techniques (3 Days)
The course is aimed at anyone who wants to develop an understanding of theory and techniques in protein purification using fast protein liquid chromatography (FPLC) on an AKTA Avant. This training course will also focus on AKTA maintenance and cleaning, and the applications of using FPLC.
The 3-day course consists of lectures, practical demos and hands-on exercises, and is hosted by Industrial Biotechnology Innovation Centre (IBioIC). Trainees will be issued a Certificate of Completion of the training by IBioIC.
Learning outcomes:
Understand the theory behind protein purification techniques
Be aware of the applications of protein purification
Purify green fluorescent protein (GFP) using hydrophobic interaction chromatography (HIC)
Learn how an AKTA system works, how to prepare for a chromatography run, and how to ensure your AKTA system remains clean
Understand the importance of good column packing
Who will benefit:
Anyone who would like to start to use AKTA systems or wants to gain an understanding of the theory behind chromatography.
Course dates:
16 - 18 September 2025
21 - 23 April 2026
To find out more and book a place, email scaleup@ibioic.com
Advanced Downstream Bioprocessing: From Harvest to Purity (3 Days)
This 3-day hands-on training course is designed for professionals and researchers looking to develop expertise in downstream bioprocessing, covering key techniques such as Disc-stack Centrifugation, High-pressure Homogenization, Tangential Flow Filtration (TFF), and Chromatography. Participants will gain a strong theoretical foundation along with practical experience in operating industry-relevant equipment, optimizing process parameters, and troubleshooting common challenges.
The course includes lectures, practical demonstrations, and hands-on exercises hosted by the Industrial Biotechnology Innovation Centre (IBioIC). By the end of the training, attendees will have the skills and confidence to apply downstream processing techniques in real-world bioprocessing applications. A certificate of completion will be awarded upon successful participation.
Learning outcomes
Understand key downstream processing techniques: Disc Stack Centrifugation, High-pressure Homogenization, Tangential Flow Filtration (TFF) and Chromatography
Gain hands-on experience in operating lab-scale equipment for each downstream processing technique and learn how to optimize key process parameters.
Learn Chromatography principles and best practices for column packing, sample loading, and gradient elution for effective purification of target molecules.
Develop skills in monitoring and analyzing process performance through real-time data collection, SDS-PAGE analysis, and protein quantification.
Who will benefit?
Scientists, engineers, graduates, technical managers and operators, especially those in their early careers in downstream bioprocessing
Anyone who would like to start using downstream processing equipment or wants to gain an understanding of the theory behind downstream processing techniques
Course dates:
03 - 05 December 2025
To find out more and book a place, email scaleup@ibioic.com
Pilot-Scale Upstream Bioprocessing: 300L Bioreactor training (4 Days)
This 4-day intensive training course is designed for professionals and researchers looking to advance their expertise in large-scale upstream bioprocessing, with a focus on scale-up to 300 L pilot-scale operations. Participants will explore the principles and practical steps involved in scaling microbial cell culture to production-relevant volumes, supported by expert-led lectures, live demonstrations, and hands-on training.
Key topics include process design and parameter translation, bioreactor preparation, sterilisation protocols, inoculation procedures, online monitoring, and harvest strategies. Hosted by the Industrial Biotechnology Innovation Centre (IBioIC), this course offers participants the opportunity to operate a 300 L stainless steel stirred-tank bioreactor, providing practical experience that bridges laboratory knowledge with industrial application.
Upon completion, attendees will have the technical skills and confidence to manage upstream processes at pilot scale. A certificate of completion will be awarded to all successful participants.
Learning outcomes
Understand the principles and challenges of scaling upstream bioprocesses from bench-scale to 300 L pilot-scale operations.
Gain hands-on experience in preparing, sterilising, inoculating, monitoring, and harvesting using a 300 L stainless steel bioreactor.
Learn how to translate key process parameters to maintain culture performance and product quality during scale-up.
Develop skills to troubleshoot large-scale upstream processes and apply effective monitoring and control strategies.
Who will benefit?
Scientists, engineers, graduates, technical managers, and operators, particularly those beginning or advancing their careers in upstream bioprocessing.
Individuals seeking practical experience in operating large-scale bioreactors or looking to enhance their understanding of upstream scale-up strategies.
Course dates:
7 - 10 October 2025
To find out more and book a place, email scaleup@ibioic.com
BioProcess360: Integrated Upstream and Downstream Bioprocessing training (5 Days)
BioProcess360: Integrated Upstream and Downstream Bioprocessing Training
This 5-day comprehensive training course offers an end-to-end exploration of the biomanufacturing process, integrating both upstream and downstream operations into a unified, hands-on learning experience. Participants will begin by cultivating a recombinant protein using a microbial expression system in a 30 L stainless steel stirred-tank bioreactor, gaining direct experience in bioreactor setup, sterilisation, inoculation, monitoring, and harvest procedures.
The course then transitions to downstream processing, where participants will apply industry-relevant techniques including disc-stack centrifugation, high-pressure homogenisation, tangential flow filtration (TFF), and chromatography to recover and purify the expressed protein. With a balanced focus on theoretical grounding and practical application, this course is ideal for professionals seeking a complete understanding of the bioprocessing workflow—from cell culture through to purified product.
A certificate of completion will be awarded upon successful participation.
Learning outcomes
Gain hands-on experience in upstream processing by cultivating recombinant protein in a 30 L bioreactor, focusing on preparation, sterilisation, inoculation, and real-time monitoring.
Understand the full bioprocessing workflow, connecting upstream operations with downstream purification strategies.
Apply key downstream techniques including centrifugation, homogenisation, TFF, and chromatography to isolate and purify the target protein.
Develop skills to monitor, troubleshoot, and optimise process parameters at every stage for improved yield and product quality.
Who will benefit?
Scientists, engineers, graduates, and technical professionals interested in gaining a holistic view of biomanufacturing.
Individuals seeking to build or strengthen practical skills across both upstream and downstream bioprocessing workflows.
Course dates:
04 - 08 May 2025
To find out more and book a place, email scaleup@ibioic.com
Applied Skills in Mammalian Cell Bioprocessing (3 Days)
This 3-day hands-on training course is designed for individuals seeking to build core competencies in the cultivation and handling of mammalian cell lines within a controlled bioprocessing environment. Blending classroom-based theory with practical lab sessions, the course offers detailed exposure to the essential techniques and challenges associated with mammalian cell culture in bioreactors up to 1.5 L scale.
Participants will gain experience in cell line maintenance, media preparation, aseptic technique, and bioreactor operation—including inoculation, parameter control, viability monitoring, and contamination prevention. This training provides a strong foundation in mammalian bioprocessing, equipping attendees with the skills necessary for application in a biomanufacturing context. A certificate of completion will be awarded upon successful participation.
Learning outcomes
Develop practical skills in aseptic technique, media preparation, and the cultivation of mammalian cell lines.
Operate bench-scale bioreactors (up to 1.5 L) for mammalian cell culture, including setup, inoculation, parameter control, and harvesting.
Understand core biological and engineering principles of mammalian bioprocessing, including cell growth kinetics, viability, and productivity.
Learn to monitor and optimise critical process parameters and apply contamination control strategies to maintain product quality.
Who will benefit?
Scientists, technicians, graduates, and professionals entering or developing their roles in mammalian cell culture.
Individuals looking to gain practical experience and theoretical knowledge relevant to biomanufacturing involving mammalian systems.
Course dates:
03 - 05 March 2026
To find out more and book a place, email scaleup@ibioic.com
Bespoke training options
Contact us to discuss bespoke training options:
All training courses are subject to agreement with our standard Training Courses T&Cs